The most common adverse effects due to clindamycin toxicity are gastrointestinal or allergic. There is no antidote for clindamycin toxicity, and the adverse effects will resolve with dose adjustment or discontinuation of the antibiotic. The recommendation is to measure serum electrolytes in patients with vomiting and diarrhea.
- The length of your treatment depends on the type of infection you have and how well you respond to the medication.
- Do not take more or less of it or take it more often than prescribed by your doctor.
- Historically, anesthesiologists have worried that clindamycin could delay the effectiveness of neuromuscular blocking agents through surgeries.
- For people who have difficulty swallowing, clindamycin comes in granules that dissolve in water.
- When given intramuscularly (IM), the drug reaches peak concentrations in 1 to 3 hours.
You should refer to the prescribing information for clindamycin for a complete list of interactions. This medication may rarely cause a severe intestinal condition due to a bacteria called C. This condition may occur during treatment or weeks to months after treatment has stopped.
Clindamycin is FDA-approved to treat septicemia, intra-abdominal infections, lower respiratory infections, gynecological infections, bone and joint infections, and skin and skin structure infections. Clindamycin is also used to treat streptococcal pharyngitis, acne vulgaris, bacterial vaginosis, and severe pelvic inflammatory disease. Clindamycin is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Clindamycin is in a class of medications called lincomycin antibiotics.
This medicine may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop using this medicine. Do not take any medicine to treat diarrhea without first checking with your doctor. If you have any questions or if mild diarrhea continues or gets worse, check with your doctor.
Vaginal Yeast Infection
Clindamycin is known to cause Clostridium colitis, which extends hospital stays and increases healthcare costs. When given intramuscularly (IM), the drug reaches peak concentrations in 1 to 3 hours. Peak serum concentrations of clindamycin are attained upon completing a short-term intravenous infusion. Oral clindamycin, administered at a daily dose of 2 grams for 14 days, shows no evidence of drug accumulation. Food does not affect the bioavailability of clindamycin.
Is C. diff (Clostridium difficile) Contagious?
Doctors should only prescribe clindamycin to people who have allergies to penicillin or if they suspect that a different antibiotic would be inappropriate for that person. This lowers the risk of colitis, which is inflammation of the colon’s inner lining. Antibiotics such as clindamycin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. The dose of this medicine will be different for different patients. Follow your doctor’s orders is dmt addictive or the directions on the label.
The side effects of taking clindamycin can worsen these two conditions. It can be used once daily at bedtime for three consecutive nights. This article looks at some uses, dosages, and symptoms of clindamycin. You should begin to feel better during the first few days of treatment with clindamycin. If your symptoms do not improve or if they get celebrities with fetal alcohol syndrome worse, call your doctor. Clindamycin is metabolized predominantly by CYP3A4 hepatic enzymes, and to a lesser extent by CYP3A5, to the major metabolite clindamycin sulfoxide and minor metabolite N‑desmethylclindamycin.
What are the side effects of oral clindamycin?
However, elderly patients are more likely to have diarrhea, which may require caution and adjustment in the dose for patients receiving this medicine. Before taking clindamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. When serious side effects occur, they tend to affect people taking oral or injectable forms of clindamycin.
Treatment & Diagnosis
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use clindamycin only for the indication prescribed.
Speak to your doctor about how is ambien better than xanax for sleep drug interactions should be managed. One of the most common side effects of many antibiotics is diarrhea. Sometimes, people experience severe diarrhea when taking clindamycin.